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Van der Meijden Machines B.V. Fermentation unit/skid complete

3,000 L Complete Pilot Bioreactor / Fermentation System

Complete 3,000 L pilot-scale bioreactor installation, fully skid-mounted and integrated on a stainless-steel frame.

The complete system is built as an integrated stainless-steel skid installation, including the process vessel, pumps, piping, valves, instrumentation, control system, and auxiliary equipment. The skid is equipped with a platform and access stairs.

The installation is highly suitable for testing, developing, and optimizing fermentation processes on a pilot scale.

Main components:
- Stainless-steel conical process vessel
- Maximum working volume: 3,000 L
- Heating/cooling jacket
- Sampling connection
- Custom-built sparger for air/gas injection
- Cambridge Sensotec Rapidox 3100 off-gas analyzer
- 4 × Watson Marlow 0XZ-63L/4 dosing pumps
- Mettler Toledo InPro3250i pH sensor
- MT 6850i DO sensor
- Endress+Hauser TMR35 temperature sensor
- Aerzen blower with 7.5 kW electric motor
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- 2 × 0.2 μm PTFE air filters
- Bran+Luebbe N-K11 plunger pump
- Netzsch 4NL30A and 4NL40A progressing cavity pumps
- Recirculation system
- Complete CIP system
- Gas control system including control valves and MFCs
- PLC control system for pumps, valves, temperature, DO, and other process parameters
- SCADA system for monitoring, operation, data logging, and data export
- DO cascade control
- Complete stainless-steel skid/frame with platform and access stairs
- Vibrating sieve
- Sieve bend
- Screw press
- Aseptic capability with tank modification

The current installation is not designed as an aseptic system. However, the existing process vessel can be replaced with a suitable aseptic vessel, making it possible to adapt the installation for aseptic fermentation applications.

Including documentation and technical knowledge from the manufacturer.

In addition, all available technical knowledge regarding the installation, operation, and maintenance is available, providing an excellent basis for future commissioning, operation, and servicing.

Complete Integrated Pilot System

A highly versatile 3,000 L pilot fermentation system, combining process vessel, pumping, dosing, aeration, temperature control, CIP, process instrumentation, and advanced PLC/SCADA control in a complete stainless-steel skid-mounted installation.

An excellent solution for pilot-scale fermentation development, process testing, and optimization.

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